The primary objective of this study was to formulate and assess sustained-release tablets of Enalapril maleate utilizing various polymers, specifically Xanthan gum, Karaya gum, and HPMC K100M, employing the wet granulation method. Compatibility studies between the drug and excipients revealed no significant alterations. Fourier-transform infrared (FT-IR) retained, affirming the absence of interactions between the drug and excipients. The blend of formulations exhibited favourable flow properties, angle of repose, bulk density, and tapped density. Post-compression assessments of the prepared tablets met quality control criteria outlined in the Indian Pharmacopoeia (I.P) limits. In vitro drug release studies, conducted in simulated gastric fluid (0.1 N HCL) for the initial 2 hours and in phosphate buffer (pH 6.8) for the subsequent hours using USP apparatus II paddle method, revealed that the EM4 formulation achieved a notable drug release of 99.75% over 12 hours. Pre formulation studies were done initially and the results were found within the limits.